Eating broccoli may keep genetic skin disorder at bay

Eating broccoli is a very good idea for people suffering from a devastating genetic skin disorder, say researchers at the Johns Hopkins University School of Medicine in Baltimore, who found that a natural compound present in the green vegetable could help treat the disorder.
The disorder in question is called epidermolysis bullosa simplex (EBS), which results from mutations in the genes encoding keratin 5 or keratin 14. The mildest form of EBS leads of blistering of the hands and feet since these are most susceptible to frequent abrasion.
Researchers led by Pierre Coulombe found that the compound sulforaphane whose natural precursors are found at high levels in broccoli and other cruciferous vegetables can help meat the disorder.
Coulomb end colleagues turned to sulforaphane in their search for a chemical activator that would induce the production of missing keratins in basal epidermis.

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